OxThera’s current pipeline is built around exploring the therapeutic potential of Oxabact’s unique properties as an activated bimodal enteric biotherapy. While we are pursuing this approach in Primary Hyperoxaluria as the lead indication, we believe there are also further diseases that could benefit from enteric biotherapy.

Oxthera utvecklar ny behandling för patienter med den livshotande njursjukdomen primär hyperoxaluri. Patienterna är oftast barn och när de inom

Single User $5500.00. Multi User $6600.00. The pipeline guide evaluates Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. The pipeline guide encapsulates all the dormant and discontinued pipeline projects. Precision medicine treatments for patients with highly aggressive malignancies. OxThera currently has two products in its pipeline: Oxabact ® for the treatment of Primary Hyperoxaluria, and Oxazyme ®, for the prevention of oxalate absorption and recurring kidney stones in Secondary Hyperoxaluria. OxThera operates through the head office in Stockholm, Sweden, and its subsidiary OxThera … COO of OxThera AB Email: elisabeth.lindner@oxthera.com www.oxthera.com.

OxThera currently has two products in its pipeline: Oxabact ® for the treatment of primary hyperoxaluria, and Oxazyme ® , an oxalate decarboxylase, for the prevention of oxalate malabsorption and recurring kidney stones in enteric hyperoxaluria. Primary Hyperoxaluria DRUG DEVELOPMENT PIPELINE OVERVIEW The “Primary Hyperoxaluria pipeline Research Monitor, 2020” report is an analytical research study on the progress achieved by pipeline companies during the year along with its historical development, current status, and outlook. Product pipeline Glepaglutide (SBS) Dasiglucagon (rescue) Dasiglucagon (pump) Dasiglucagon (CHI) GLP-1/glucagon dual-acting agonist Orphan drug designation Pipeline drugs such as Zealand Pharma’s Glepaglutide (ZP1848), a long acting GLP-2 analog for short bowel syndrome, is in phase III clinical trials, results of which is expected in 2021. Pipeline drugs for short bowel syndrome act as a driver for the short bowel syndrome market. The Oxalosis & Hyperoxaluria Foundation facilitates the development of promising new drugs, and the drug development pipeline enables you to track the progress of these potential therapies.

Not only are there several clinical trials studying therapies to treat the underlying cause of primary hyperoxaluria, many trials are also exploring ways to treat key symptoms of both primary and enteric (or secondary) hyperoxaluria and improve quality of life. OxThera currently has two products in its pipeline: Oxabact ® for the treatment of Primary Hyperoxaluria, and Oxazyme ®, for the prevention of oxalate malabsorption and recurring kidney stones OxThera currently has two products in its pipeline: Oxabact ® for the treatment of primary hyperoxaluria, and Oxazyme ®, an oxalate decarboxylase, for the treatment of oxalate malabsorption and Alnylam has a deep pipeline of investigational medicines, including six product candidates that are in late-stage development.

Pipeline Utilizing the special features of an active bimodal enteric biotherapy, Oxabact® could provide the first orally administered treatment to tackle primary hyperoxaluria, by promoting active secretion of oxalate from plasma into the gut and degrading it there.

Strong pipeline drugs for short bowel syndrome are anticipated to provide tremendous growth opportunities for the market in the near future. Pipeline drugs such as Zealand Pharma’s Glepaglutide (ZP1848), a long acting GLP-2 analog for short bowel syndrome, is in phase III clinical trials, results of which is expected in 2021. The "Primary Hyperoxaluria Pipeline Research Monitor, 2020 - Drugs, Companies, Clinical Trials, R&D Pipeline Updates, Status and Outlook" report has been added to ResearchAndMarkets.com's offering. The pipeline is composed of several programs, with the potential lead program being for HER-2 expressing tumors.

This drug pipelines features 8 companies, including Alnylam Pharmaceuticals, OxThera, Dicerna Pharmaceuticals, Inc., Allen Pharmaceuticals, Biocodex, Federation Bio

The pipeline guide encapsulates all the dormant and discontinued pipeline projects. Athera Biotechnologies AB is a dynamic company with a vision to address the need for improved treatment of vascular disease patients. We are now pursuing clinical development with our anti-inflammatory antibody. Xbrane is a commercial phase Swedish biopharmaceutical company specialized in biosimilars and long-acting injectables.

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Product pipeline Glepaglutide (SBS) Dasiglucagon (rescue) Dasiglucagon (pump) Dasiglucagon (CHI) GLP-1/glucagon dual-acting agonist Orphan drug designation OxThera is a biopharmaceutical company with products in late stage clinical development focusing on Primary and Secondary Hyperoxaluria. OxThera currently has two products in its pipeline: Oxabact® for the treatment of Primary Hyperoxaluria, and Oxazyme®, an oxalate decarboxylase, for dietary hyperoxaluria and prevention of kidney stones STOCKHOLM, Sweden I March 14, 2018 I OxThera AB, a Stockholm-based privately-held biopharmaceutical company with a product in late stage clinical development focusing on Primary hyperoxaluria (PH), announces the randomization of the first patient into its phase III study, EPHEX, with Oxabact. OxThera holds worldwide rights for compositions and methods of use for treatment of hyperoxaluria. OxThera currently has two products in its pipeline: Oxabact ® for the treatment of primary hyperoxaluria, and Oxazyme ® , an oxalate decarboxylase, for the prevention of oxalate malabsorption and recurring kidney stones in enteric hyperoxaluria.
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18 Mar 2021 Oxalobacter formigenes is an anaerobe, non-pathogenic bacterium which exclusively uses oxalate as the energy source. OxThera has taken this

pipeline och bygga en självbärande FoU-portfölj. Detta är Sobi .4 tör i OxThera AB. Ledamot i styrelsen. Svag pipeline – många av de behandlingar som efterfrågas innebär radikal förnyelse Sweden, MIPS, NeuroNova, Optivy, Orexo, OxThera och Ultrazonix DNT. Vår kliniska pipeline består för närvarande av två program, SOBI002 OxThera AB, NVC Holding. AB, Hydragyr AB, LTB4. Sweden AB, CC10 attraktiv egen pipeline och intäkter från de framgångsrika projekt Property AB och OxThera Inc. Styrelseordförande i Biosource. Europe AB. bolagets pipeline i den takt som bedöms lämplig, genom att blanda positioner inom Pharmacia, Quintiles, Orexo, Oxthera och Q-Med samt och ger bolaget utmärkta möjligheter att bredda sin pipeline positioner inom Pharmacia, Quintiles, Orexo, Oxthera och Q-Med samt som vd https://www.di.se/pressreleaser/2019/6/27/oxthera-oxthera-presenterar-fortsatt-starka- https://www.di.se/live/klart-for-ny-kontroversiell-pipeline-lundin-jublar/ 11.

Figur 4. Vicores pipeline för fortsatt utveckling av VP01 och VP02. Figur 3. Healthcare AB. Styrelseordförande och styrelseledamot i OxThera.

Legal disclaimer Privacy policy. We have developed a pipeline of first-in-class, oral, non-absorbed enzyme therapeutic candidates to treat patients with rare and severe metabolic disorders that affect the kidney. Our lead product candidate, reloxaliase (formerly ALLN-177), is an oral enzyme therapeutic that we are initially developing for the treatment of enteric hyperoxaluria in adults. The company has late-stage products in development, including an inhaled formulation of AAT for the treatment of AAT deficiency, and in addition, its intravenous AAT is in development for other indications, such as GvHD, prevention of lung transplant rejection and type-1 diabetes.

OxThera currently has two products in its pipeline: Oxabact ® for the treatment of primary hyperoxaluria, and Oxazyme ®, an oxalate decarboxylase, for the treatment of oxalate malabsorption and kidney failure in enteric hyperoxaluria. Primary Hyperoxaluria - Pipeline Review, H2 2017. Summary. Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Primary Hyperoxaluria - Pipeline Review, H2 2017, provides an overview of the Primary Hyperoxaluria (Genito Urinary System And Sex Hormones) pipeline landscape. OxThera is a biotechnology company active in the development of products for the treatment of metabolic disorders resulting from excess levels of oxalate from endogenous and exogenous sources.